Isolation transformer with network analyser

Hello,

I want to drive a network analyser over an isolation transformer.
Thus the shields of the cables have no connection to earth.
Are there any problems/difficulties with this set up?

"drive" means supply power, I presume. Shouldn't be a problem in terms of RF specifications.

Thx for the reply.
Yes, the network analyser is connected over an isolation transformer with the main power. This should avoid a ground loop.